Tottenham’s survival hopes took a turn for the worse after a nightmare 24 hours concluded with a 3-1 home defeat to Crystal Palace.
Relegation is now a serious possibility for Spurs, who are just one point outside the bottom three of the Premier League table after defeat to Palace.
The loss comes after and with Manchester City on Wednesday, while the Premier League's bottom team Wolves have now also won back-to-back games over Aston Villa and champions Liverpool, giving themselves a glimmer of a miracle survival.
Wolves are the form side of the bottom six and have a favourable run-in, which gives them hope of not finishing bottom.
They are three points behind second-bottom Burnley, who are nine points from safety, while West Ham occupy the final relegation spot in 18th on goal difference.
Tottenham are one point ahead of the Hammers and Forest in 16th, while Leeds remain two points ahead of Spurs and three from the drop zone, but will be nervously looking over their shoulders.
With six teams fighting to avoid relegation, Your Site keeps track of the battle for survival…
The fixture list is in Leeds and Wolves' favour based on the opposition's league position, with Spurs, Forest, West Ham and Burnley all having more difficult games left to play. If Wolves win every game, they will reach the 40-point mark.
There are some crucial clashes between relegation rivals in the last three months of the season, with Leeds facing four of the bottom six in their final six fixtures, including a final-day trip to West Ham.
Here are the six-pointers that could be key in deciding the relegation battle:
After the results this midweek, Wolves remain the slight favourites at 99.91 per cent to be relegated, closely followed by Burnley (99.51 per cent).
After their win at Fulham, West Ham have moved on to 49.94 per cent chance of being relegated. The Opta supercomputer has given Forest a 28.27 per cent chance of going down, along with 13.94 per cent for Spurs and 8.31 per cent for Leeds.
In the last nine Premier League seasons, teams finishing on 36 points or more have avoided relegation.
Last season, 26 points would have been enough to stay up as an exceptionally poor bottom three of Leicester, Ipswich and Southampton all made an immediate return to the Championship.
Spurs took advantage of the trio's weaknesses to focus on winning the Europa League as they finished a dismal 17th on 38 points - 13 points above 18th-placed Leicester.
But that luxury for Tottenham is not there this season as they face the very real possibility of relegation to the second tier of English football for the first time since 1977.
With the teams involved in the relegation fight significantly stronger than last season, the 40-point mark could well be being eyed up.
Only three teams have been relegated with 40 points or more in the 20-team Premier League era - Sunderland (1996/97), Bolton (1997/98) and West Ham (2002/03) - the latter holding the record for the team relegated with the most points with 42.
Leeds have lost back-to-back home games and have won just once in their last seven games, leaving them 15th and three points off the bottom three.
Daniel Farke's side have won just once on the road in the league - a victory at Wolves in September - adding extra importance to their games at Elland Road.
"It would be the shock of the century. It would be absolutely mind-blowing to think that they could disappear out of this league, but I don't think they will."
Even if Gary Neville is confident the Premier League ever-presents will not be relegated, their form says otherwise, with Spurs sitting 16th and one point from the drop.
Igor Tudor's side are on a club-record equalling 11-game winless Premier League run, they are yet to win in 2026 and are battling a crippling injury crisis.
Nottingham Forest are now one point behind Spurs after a 2-2 draw at Manchester City on Wednesday, although they remain without a win in six league matches.
Vitor Pereira is yet to win any of his league games in charge, and earlier this week, pointed to an intense fixture list - including Europa League games - that he feels his squad is struggling with.
West Ham looked doomed at the start of the year before a huge win at rivals Tottenham kickstarted their survival bid. They have also beaten another relegation rival in Burnley since then, and picked up another huge win at Fulham on Wednesday.
The Hammers have lost only twice since in eight games since that victory in north London, giving them hope of avoiding relegation for the first time since 2011.
Burnley look likely for an immediate return to the Championship.
Scott Parker's side are nine points from safety and have only won one of their last 20 league games.
A 19-game winless start to the Premier League season seemed to have sealed Wolves' fate.
However, two victories on the spin means the Old Gold, who are 12 points from safety, need less of a major miracle to stay in the top flight for a ninth season.
